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Found 3 of ec50 for PROTEIN CEREBLON
having polymerids = 1271,50007050 and
complexids = 339,6,50002377
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50404378(CHEMBL5275511)
Affinity DataEC50:  79nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50404379(CHEMBL5184599)
Affinity DataEC50:  703nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA-binding protein Ikaros/Protein cereblon(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50557457(CHEMBL4742712)
Affinity DataEC50: >1.00E+4nMAssay Description:Protac activity at CRBN/IKZF1 (unknown origin) assessed as IKZF1 degradationMore data for this Ligand-Target Pair